Product ID:ELASE-CHLOROMYCETIN OINTMENT
MSDS Date:06/13/1991
FSC:6505
NIIN:00-126-2039
MSDS Number: BRBZP

PARKE-DAVIS DIV OF WARNER-LAMBERT CO

201 TABOR RD
MORRIS PLAINS, NJ 07950-2614
US

Emergency Phone: 201-540-2000

Info Phone: 201-540-2000

Preparer: ROY MUELLER

Cage: 82559

WARNER-LAMBERT CO

MORRIS PLAINS, NJ 07950-2614 US

Telephone: 201-540-2000

Cage: 82559

FIBRINOLYSIN (EXTRACTED FROM BOVINE BLOOD) *93-1*

CAS: 9001-90-5

DESOXYRIBONUCLEASE (EXTRACTED FROM BOVINE PANCREAS OR

CAS: 9003-98-9

RTECS: RF0750000

CHLORAMPHENICOL (SUSPECTED HUMAN CARCINOGEN BY IARC)

CAS: 56-75-7

RTECS: AB6825000

Routes of Entry: Inhalation:YES Skin:YES Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:YES OSHA:NO
Health Hazards Acute and Chronic:COMBINATION OF THESE TWO LYTIC ENZYMES
MAY CAUSE AN ALLERGIC REACTION IN PERSONS SENSITIVE TO MATERIALS OF
BOVINE ORIGIN. SIDE EFFECXTS TO THE ENZYMES HAVE NOT BEEN A PROBLEM
AT THE DOSE RECOMMENDED F OR ELASE. EYES: IRRITATION. SKIN:
DERMATITIS, ERYTHEMA & EDEMA.
Explanation of Carcinogenicity:SEE INGREDIENTS
Effects of Overexposure:THERAPEUTIC ADVERSE REACTIONS INCLUDE BONE
MARROW DEPRESSION, SERIOUS & FATAL BLOOD DYSCRASIAS (APLASTIC
ANEMIA, HYPOPLASTIC ANEMIA, THROMBOCYTOPENIA & GRANULOCYTOPENIA),
GASTROINTESTINAL & CNS DISTRU BANCES. MARROW DEPRESSION CAN BE
REVERSIBLE (DOSE RELATED) & IRREVERSIBLE (NOT DOSE RELATED). SEE
SUPPLEMENTAL DATA.
Medical Cond Aggravated by Exposure:SENSITIVITY

First Aid:EYES: FLUSH W/WATER FOR 15 MINS. SKIN: WASH W/SOAP & WATER
UNTIL FREE OF RESIDUE. INHALATION: REMOVE TO FRESH AIR. INGESTION:
OBTAIN MEDICAL ATTENTION IN ALL CASES.

Extinguishing Media:CO2, DRY CHEMICAL, FOAM, WATER SPRAY
Fire Fighting Procedures:USE APPROVED SELF CONTAINED BREATHING
APPARATUS.

Spill Release Procedures:COLLECT SPILLED MATERIAL. WASH ALL
CONTAMINATED SURFACES W/SOAP & WATER. PLACE WASTE IN APPROPRIATE
LABELED, SEALED CONTAINER FOR FUTURE DISPOSAL.

Handling and Storage Precautions:STORE AS STATED IN PRODUCT LABELING.
Other Precautions:MATERIAL SHOULD BE HANDLED IN SUCH A WAY AS TO AVOID
SKIN & EYE CONTACT.

Work Hygienic Practices:WASH EXPOSED SKIN PROMPTLY. REMOVE/LAUNDER
CONTAMINATED CLOTHING & WASH CONTAMINATED PROTECTIVE EQUIPMENT
BEFORE REUSE.
Supplemental Safety and Health
OVEREXPOSURE CON'T: THERE HAVE BEEN REPORTS OF APLASTIC ANEMIA
ATTRIBUTED TO CHLORAMPHENICOL WHICH LATER TERMINATED IN LEUKEMIA.

Appearance and Odor:WHITE, OPALESCENT, SOFT, GRITTY OINTMENT, ODORLESS.

Stability Indicator/Materials to Avoid:YES
Hazardous Decomposition Products:CO, CO2, NITROGEN & HYDROGEN CHLORIDE

Waste Disposal Methods:DISPOSE OF IN ACCORDANCE W/LOCAL, STATE, &
FEDERAL REGULATIONS. INCINERATION IN A PERMITTED INCINERATOR IS THE
PREFERRED DISPOSAL METHOD.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.